Bartender Euclid O’Brien and his assistant, Harry McLeod are about to become the effect of a special elixir sent by Euclid’s brother from Borneo. However, the effect will vary dramatically—McLeod growing as tall as an 18-story building while O’Brien ends up in miniature. To make things worse, a mobster who has come to shake down the bar drinks a cocktail that contains the elixir and promptly shrinks.
Not happy at being “taken down to size” the mobster decides to kill O’Brien. Meanwhile, O’Brien has a bigger problem—figuring out how to rescue McLeod who is clinging to the side of a New York City high-rise before his legs give out from under him.